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Hepatitis, myocarditis, and encephalitis are treated symptomatically Rupture of the spleen requires splenectomy and is most often caused by deep palpation of the spleen or vigorous activity Patients should avoid contact or collision sports for at least 4 weeks to decrease the risk of splenic rupture (even if splenomegaly is not detected by physical examination which can be insensitive)

Lesions suspected to be basal cell carcinomas should be biopsied, by shave or punch biopsy Therapy is then aimed at eradication with minimal cosmetic deformity, often by excision and suturing with recurrence rates of 5% or less The technique of three cycles of curettage and electrodesiccation depends on the skill of the operator and is not recommended for head and neck lesions After 4 6 weeks of healing, it leaves a broad, hypopigmented, at times hypertrophic scar Radiotherapy is effective and sometimes appropriate for older individuals (over 65), but recurrent tumors after radiation therapy are more difficult to treat and may be more aggressive Radiation therapy is the most expensive method to treat basal cell carcinoma and should only be used if other treatment options are not appropriate Mohs surgery removal of the tumor followed by immediate frozen section histopathologic examination of margins with subsequent reexcision of tumor-positive areas and final closure of the defect gives the highest cure rates (98%) and results in least tissue loss It is appropriate therapy for tumors of the eyelids or for recurrent lesions, or where tissue sparing is needed for cosmesis Patients with basal cell carcinomas must be followed to detect new or recurrent lesions

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Rubin AI et al Basal-cell carcinoma N Engl J Med 2005 Nov 24;353(21):2262 9 [PMID: 16306523]

Each part of the for loop header is optional. You can, for example, initialize the value outside the for loop, as shown in Example 5-18.

Pruritic, violaceous, flat-topped papules with fine white streaks and symmetric distribution (Plate 24) Lacy lesions of the buccal mucosa Commonly seen along linear scratch marks (Koebner phenomenon) on anterior wrists, penis, legs Histopathologic examination is diagnostic

Nonhealing ulcer or warty nodule (Plate 23) Skin damage due to long-term sun exposure Common in fair-skinned organ transplant recipients Squamous cell carcinoma usually occurs subsequent to prolonged sun exposure on exposed parts in fair-skinned individuals who sunburn easily and tan poorly It may arise from an actinic keratosis The lesions appear as small red, conical, hard nodules that occasionally ulcerate The frequency of metastasis is not precisely known, though metastatic spread is said to be less likely with squamous cell carcinoma arising out of actinic keratoses than with those that arise de novo In actinically induced squamous cell cancers, rates of metastasis are estimated from retrospective studies to be 3 7% Squamous cell carcinomas of the lip, oral cavity, tongue, and genitalia have much higher rates of metastasis and require special management

Let s look at the user interface for the program. Open the Resource group in the Groups & Files pane and double-click on MainMenu.nib to launch Interface Builder and open the file. Next, click on the Instance tab and double-click on the Window icon. I built the MemoryTracker user interface by dragging each interface component from the Interface Builder palette to the appropriate location within its tabbed view (see figure 7.9). Table 7.6 lists the control types for the various interface objects.

Lichen planus is an inflammatory pruritic disease of the skin and mucous membranes characterized by distinctive papules with a predilection for the flexor surfaces and trunk The three cardinal findings are typical skin lesions, mucosal lesions, and histopathologic features of band-like infiltration of lymphocytes in the dermis The most common drugs causing lichen planus-like reactions include gold, sulfonamides, tetracycline, quinidine, NSAIDs, and hydrochlorothiazide Hepatitis C infection is found with greater frequency in lichen planus patients than in controls Allergy to mercury amalgams can trigger oral lesions identical to lichen planus

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