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Disruption is an interesting word In the language of Harvard Business School professor Clayton M Christensen (The Innovator s Dilemma, Harvard Business School Press, 1997), disruptive technologies represent innovations that appeal to emerging markets not existing ones They reinvent a whole new standard for how products and services operate, perform, and how customers use them, reshaping markets by changing equations for productivity, even life style Disruptive technologies, however, start out as innovations that result in worse product performance than existing sustaining technologies Classically, disruptive technologies under-perform established products in mainstream markets But they have features think of the earliest wireless handsets and web phones that a few fringe customers value highly Over time, products based on disruptive technologies reshape thinking; they cater to hidden needs; they suggest new ways of acting and transacting Typically these products are cheaper, simpler, smaller, and frequently, more convenient to use than existing technologies So, for example, just as the PC supplanted the minicomputer, so the laptop created a fresh market for computing on the go Wireless in turn created mobile talking, then mobile data And today, thanks to more powerful microprocessors and the advent of better networks with more flexible bandwidth allocation, wireless offers the promise of access to multimedia data, voice, and video on the fly, in real-time The shrunken form factors for wireless devices suggest a very personal, close to the body form of communication with fast response times and high levels of security imagined or real These are attributes that 21st century business people and consumers value and are beginning to demand Today, for example, without even being conscious of it, wireless users are altering their life styles in the name of becoming accessible and connected, even while moving through time and space Many are using e-mail incessantly instead of picking up a telephone Many prefer to send one-way messages rather than tie up hours in emotional, interactive conversations Since those who phone in cars are prone to distraction and traffic accidents, some now prefer taking their calls through voice recognition services and hands-free devices Others are sending wireless messages through smart phones, Palm-connected organizers, and two-way.

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Using iTextSharp is possible you need to set the version of PDF and then ... CompressionLevel = PdfStream. ... SetFullCompression (); stamper.

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C# ( PDF Compression ) Big PDF file to Small PDF . Can you help me.

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Innovate without complicating This isn t a universal prescription: An organization at death s door may have to innovate every which way (and may still go through the door) But innovations must reflect people s limited capacities to learn and to change Be fair and realistic

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Figure 1 6 The renal microcirculation The kidney is divided into a corPericyte tex and a medulla The cortex contains an arterial network, glomeruli, a dense peritubular capillary plexus, and a venous drainage system In the DVR cortex, arcuate arteries, which run parallel to the surface, give rise to H2O cortical radial (interlobular) arteries NaCl radiating toward the surface Afferent Endothelial Urea cell arterioles originate from the cortical radial arteries at an angle that varies with cortical location Blood is supplied to the peritubular capillaries of the cortex from the efferent flow out of superficial glomeruli Blood is supplied to the medulla from the efferent flow out of juxtamedullary glomeruli Efferent arterioles of juxtamedullary glomeruli give rise to bundles of descending vasa recta in the outer stripe of the outer medulla In the inner stripe of the outer medulla, descending vasa recta and ascending vasa recta returning from the inner medulla run side by side in the vascular bundles, allowing exchange of solutes and water as described in 6 The descending vasa recta from the bundle periphery supply the interbundle capillary plexus of the inner stripe, whereas those in the center supply blood to the capillaries of the inner medulla Contractile pericytes in the walls of the descending vasa recta regulate flow DVR, descending vasa recta AVR, ascending vasa recta (Used with permission from Pallone TL, Zhang Z, Rhinehart K Am J Physiol Renal Physiol 2003;284:F253 F266)

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Compress PDF File Size in ASP.Net using C# and VB.Net | ASPForums.Net
Dim stamper As New PdfStamper(reader, New FileStream( "C:\Users\ dharmendra\Desktop\test1. pdf " , FileMode.Create), PdfWriter.

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Consider these trends for the future: Wireless data replaces guesswork: Interactive wireless conversations happen between people and between inanimate systems Invisible wireless devices are being implanted in rockets and under skin; in vending machines, ambulances, police cars, and taxicabs; in laptop computers, earthquake detectors and underwater reservoirs, field service trucks, L utility meters, oil derricks, and nuclear RE power plants Wireless data drives WI tractor-trailers, cash regisR ters and autoFO

For all of these reasons, and more, my father was loath to depart from his game plan Still, he would tip his hat to the inevitability of change, especially over the long term

reNaL FUNCtIONS, aNatOMY, aND BaSIC prOCeSSeS / 15

One must not hesitate to innovate and change with the times and the varying formations The leader who stands still is not progressing, and he will not remain a leader for long

Nephrons are categorized according to the locations of their renal corpuscles in the cortex (see Figure 1 5): (1) In superficial cortical nephrons, renal corpuscles are located within 1 mm of the capsular surface of the kidneys; (2) in midcortical nephrons, renal corpuscles are located, as their name implies, in the midcortex, deep relative to the superficial cortical nephrons but above (3) the juxtamedullary nephrons, which, as mentioned previously, have renal corpuscles located just above the junction between cortex and medulla One major distinction among these 3 categories of nephrons is the length of Henle s loop All superficial cortical nephrons have short loops, which make their hairpin turn above the junction of outer and inner medulla All juxtamedullary nephrons have long loops, which extend into the inner medulla, often to the tip of a papilla Midcortical nephrons may be either short looped or long looped The additional length of Henle s loop in long-looped nephrons is due to a longer descending thin limb and the presence of an ascending thin limb Finally, the beginning of the thick ascending limb marks the border between the outer and inner medulla; in other words, the thick ascending limbs are found only in the cortex and outer medulla

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