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This method is useful for select individuals NPT testing takes advantage of the fact that men with normal erectile function have 4 6 episodes of involuntary, nocturnal erections lasting 20 50 minutes during a 6 8 hour sleep cycle These erections occur mostly during REM (rapid eye movement) sleep NPT testing in the diagnosis of ED has been described and is known worldwide [50] NPT is best used to distinguish between organic and psychogenic ED Other simple and inexpensive methods such as the stamp test [51], the snap gauge band [52], and the erectiometer [53], were developed originally to record nocturnal erections The common drawback of all these methods was that they could only record one nocturnal event Thus no information could be obtained on the duration and frequency of nocturnal

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6 SPACE could be useful in the diagnosis of autonomic neuropathy of the cavernous and/or myopathy of the cavernous muscles [56] Based on the results obtained in 214 patients with ED, and 39 normally-potent patients, they observed that 52% of all impotent patients had pathologic results in SPACE Further re nement of this method showed that surface electrodes as well as conventional concentric needle electrodes could be used to measure the electrical activity of the cavernous nerves With respect to the present status of CCEMG, it may be concluded that this method can detect abnormalities in cavernous muscle to a certain extent, although these pathologic alterations can be attributed to both damage to autonomic penile innervation and to degenerative processes of the cavernous smooth muscle There are indications that CCEMG amplitudes correlate with the density of the cavernous smooth muscle To date, there are no generally accepted standard criteria that would enable exact differentiation between normal and pathologic, and etiologic classi cation of the various ED forms is not possible Thus, despite the fact that CCEMG has been around for 10 20 years, it is still considered experimental It is far from becoming a routine procedure in the evaluation of ED etiology, especially in terms of autonomic neuropathy

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Note 3 Jane Person owns options to acquire 4,000 shares of stock of Winner Corp at an option price of $5 per share The option expires on June 30, 20X5 The estimated current value is its published selling price Note 4 The investment in Kenbruce Associates is an 8% interest in a real estate limited partnership The estimated current value is determined by the projected annual cash receipts and payments capitalized at a 12% rate Note 5 James Person owns 50% of the common stock of Davekar Company, Inc, a retail mail order business The estimated current value of the investment is determined by the provisions of a shareholders agreement, which restricts the sale of the stock and, under certain conditions, requires the company to repurchase the stock based on a price equal to the book value of the net assets plus an agreed amount for goodwill At December 31, 20X3, the agreed amount for goodwill was $112,500, and at December 31, 20X2, it was $100,000 A condensed balance sheet of Davekar Company, Inc, prepared in conformity with generally accepted accounting principles, is summarized below: Exhibit 412

erections, and the degree of erection could not be suf ciently quanti ed The introduction of a computerized system called Rigiscan made it possible to measure both tumescence and rigidity during an 8-h sleep cycle Interpretation of Rigiscan results has been simpli ed by new, more extensive software (Rigiscan plus), which includes four new parameters In the Rigiscan , which is the most commonly-used device to measure NPT worldwide, two loops at the penile base and tip (coronary sulcus) are contracted every 20 sec to constantly record and store circumference and rigidity changes, ie the erection status A personal computer can then be used to print out the data [54]

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