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Another NBCR-funded project is the PDB CE Grid Computing Web Portal [32], which enables users to perform structural comparisons of proteins using the CE algorithm on HPC resources at NPACI Like GAMESS, the CE portal can be accessed from any Web browser The CE Portal gives users on-line capabilities to upload input les to query the CE database, submit searches to the CE database, display a status of the database searches, and view results of the searches The portal enables users to upload their input les that contain representations of their proteins The user can select a speci c protein chain and query a CE database against it The query looks for similar protein structures and aligns the proteins so that the user can view similarities and differences It is distinct from the other portals because it allows two forms of login: anonymous and registered.

With a little work it is possible to pull out key points, such as the number of people living in New York is obviously quite high, but making comparisons can be quite difficult. Two columns were added to the table: the latitude and longitude of each city shown. Otherwise, the data used is exactly as shown here.

Because either Macintosh or Windows users can use FileMaker Pro template and database files, Windows users must occasionally unstuff Macintosh StuffIt archives. To handle this situation, you can download a free copy of StuffIt Expander for Windows (Allume Systems) from www.allume.com. If you don t have file extraction utilities, you can download many of the most popular ones from www.allume.com (StuffIt Expander) and www.winzip.com (WinZip).

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When you import data into FileMaker Pro, you bring that data in from another program s data files. FileMaker Pro can import data from many popular Mac and PC programs data file formats, such as dBASE, FoxBASE/FoxPro, AppleWorks, and Microsoft Excel. You can also import data from another FileMaker Pro database even one created on a different type of computer. You can import data into FileMaker Pro in four ways: You can open a non-FileMaker file by using the File Open command, automatically converting it en masse to a new FileMaker Pro database. (Data files from certain applications, such as Microsoft Excel, can also be opened by being dropped onto the FileMaker Pro 8 application icon.) If you already have a FileMaker Pro database, you can use the File Import Records submenu command to import records from another FileMaker Pro database or from a file created in a different program. Better yet, starting with FileMaker Pro 8 Advanced (sorry, not available in the base product), you can import tables directly from another FileMaker Pro database, obviating the need to manually create the table into which you want to import records. FileMaker Pro can also import pictures directly from a connected digital camera or similar device (Mac only) as well as import an entire folder of image or text files. You can take advantage of FileMaker s Open Database Connectivity (ODBC), Java Database Connectivity (JDBC), or XML (eXtensible Markup Language) support to import data from any compliant application, such as Microsoft Access, into an existing FileMaker Pro database. (See 21 for more information.)

The Pucker & Bloat command moves anchor points in one direction and creates two independent direction points on either side of each anchor point. The direction points are moved in the opposite direction of the anchor points, and the direction of movement is always toward or away from the center of the object. The distance moved is the only thing that you control when you use the Pucker & Bloat command. Typing a percentage moves the points that percentage amount.

121 THE NECESSITY OF CULTURING STEM CELLS Adult stem cells, by the traditional de nition, are tissue-speci c; they stay dormant until there is a need for repair, expansion, or regeneration and thus, in normal circumstances they are the major guardians of organ homeostasis To be classi ed as stem cells, they must meet the basic requirements of self-renewal and differentiation into at least one cell type [Till et al, 1964], giving rise to cells that function appropriately in their tissue of residence By and large, the ultimate proof that a cell is a stem cell requires the demonstration that a single cell, by clonal expansion, can give rise to a functional tissue in the physiological context of an animal, most often achieved through transplantation experiments in vivo Studying the biology of adult stem cells in mammals, particularly in humans, is notoriously dif cult.

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